Human Health Assessment Branch
21st Century Toxicology Seminar Series

Back to Assessing Human Health Risk

To request a copy of the available presentations, posters or abstracts, please email


  • Chemoproteomic Platforms for Mapping Novel Toxicological and Disease Mechanisms, Daniel K. Nomura, PhD, Departments of Chemistry, Molecular and Cell Biology, and Nutritional Sciences and Toxicology, University of California, Berkeley, presented May 22, 2017.
  • High-Content Screening of Chemical Toxicity in Zebrafish Embryos, David C. Volz, PhD, Department of Environmental Sciences, University of California, Riverside, presented January 20, 2017.


  • Using Mechanistic Toxicology and High Content Toxicology Screening for Prediction of Endocrine Disruption, Hepatotoxicity, Cardiotoxicity and Neurotoxicity, presented May 5, 2015.
    • Background on Cyprotex Methodology for Steroidogenesis Assay, Estrogen and Androgen Binding Assays Using AR or ER, and Validation Using T47D-KBluc (ER) and MDA-kb2 (AR), Brent Gilbert, M.Tox., Chemical and Personal Care Director, Cyprotex US, LLC, David Blakeman, M.Tox., Study Director, Cyprotex US, LLC.
    • Background on Cyprotex Methodology for Cell Systems (Types and Biology), CellCiphr Assay for Liver and Neurotoxicity, and Mechanisms of Toxicity Detected In Vitro, Christopher Strock, PhD, Associate Director, Biological Screening and Assay Development, Cyprotex US, LLC.
  • Advances in Skin Sensitization Determination with In Vitro and In Silico Models: What Can They Tell Us?, presented April 21, 2015.
    • Conducting In Vitro Investigation of Skin Sensitization Potential, Kim Norman, PhD, DABT, Institute for In Vitro Sciences, Inc.
    • Safety Assessment Methods and Strategies for Skin Sensitization Potential, Raja Settivari, PhD, DABT, Dow Chemical Company.
    • Integrated Computational Approaches to the Assessment of Skin Sensitization Potential of Chemicals, Nicole Kleinstreuer, PhD, National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods and Integrated Laboratory Systems.


  • Background on BioSeek Methodology Used in the ToxCast Program. Clarification on Cytotoxicity Effect, & Use of BioSeek, ToxCast in Pesticide Prioritization, Hazard Identification and Risk Assessments, Ellen Berg, PhD, Scientific Director and General Manager, BioSeek of DiscoveRx Corporation, presented October 29, 2014.
  • Using High-Throughput Methods to Conduct Risk-Based Prioritization of Chemicals for the EDSP, Kevin Crofton, PhD, Acting Deputy Director, National Center for Computational Toxicology, US EPA, presented April 30, 2014.
  • Rapid In Vivo Assessment of Bioactivity in Zebrafish: High Content Data for Predictive Toxicology, Robert Tanguay, PhD, Distinguished Professor, Sinnhuber Aquatic Research Laboratory, Oregon State University, presented April 30, 2014.


  • Nuclear Receptor Humanised Mouse Models to Investigate Nongenotoxic Hepatocarcinogenesis, Dr. Cliff Elcombe, Research Director, CXR Biosciences and Senior Lecturer at the Biomedical Research Center, University of Dundee Medical School, Dundee Scotland, presented January 24, 2011.