California Medical Supervision Program

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The California Medical Supervision Program is designed to protect agricultural workers who regularly handle Type I and II organophosphate (OP) and carbamate (CB) pesticides. It requires employers to contract with a medical supervisor to monitor the blood cholinesterase levels of their workers. Cholinesterase is critical for the normal function of the nervous system. Overexposure to OP and CB pesticides can lead to a depression in cholinesterase activity levels, which can lead to various adverse health effects. The California Department of Pesticide Regulation is responsible for the overall administration of the Program. The Office of Environmental Health Hazard Assessment is responsible for outreach and education of medical supervisors, and the California Department of Public Health is responsible for approving laboratories performing cholinesterase analysis.


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1001 I Street, P.O. Box 4015
Sacramento, CA 95812-4015
Phone: (916) 445-4222